Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867950 | 0.90 | NPC1 (0.38) | MCL1ALOX5NPC1RAB9AL3MBTL1 | |
| SCHEMBL9867051 | 0.86 | RAB9A (0.41) | ALOX5NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL9869017 | 0.79 | ALOX5 (0.52) | MCL1ALOX5NPC1RAB9ALMNA | |
| SCHEMBL9867836 | 0.78 | SIRT1 (0.46) | NR4A1SIRT1NPC1RAB9AL3MBTL1 | |
| SCHEMBL9868498 | 0.78 | GLRA3 (0.49) | MCL1ALOX5L3MBTL1KDM4EMEN1 | |
| SCHEMBL9867508 | 0.78 | NPC1 (0.45) | ALOX5NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL4115756 | 0.77 | GLRA3 (0.50) | NR4A1SIRT1NPC1RAB9ALMNA | |
| SCHEMBL4123639 | 0.74 | GLRA3 (0.57) | ALOX5NR4A1SIRT1NPC1RAB9A | |
| SCHEMBL11209332 | 0.71 | KMT2A (0.47) | NR4A1SIRT1NPC1RAB9AMAPT | |
| SCHEMBL9869198 | 0.69 | EDNRA (0.47) | MCL1NPC1RAB9AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006549-A | Antiinflammatory agents | MERCK & CO., INC. (US) | 1991-04-09 | — | — | US | disclosed |
| EP-0399773-A1 | Novel 7-aroyl-4-hydroxy-3-methyl benzolfurans as dual inhibitors of cyclooxygenase and 5-lipoxygenase | MERCK & CO. INC. (US) | 1990-11-28 | — | — | EP | disclosed |