SCHEMBL4148452

SCHEMBL4148452

Brc1ccc(-c2nc3cccnc3o2)cc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.54
NPC1 O15118 3/20 0.54
KDM4E B2RXH2 2/20 0.54
ALDH1A1 P00352 2/20 0.54
HPGD P15428 2/20 0.54
TP53 P04637 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
HSD17B10 Q99714 1/20 0.54
RXFP1 Q9HBX9 1/20 0.53
MAOB P27338 1/20 0.49
SGMS2 Q8NHU3 6/20 0.45
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
ADRB2 P07550 1/20 0.44
MAPT P10636 1/20 0.42
NR1H4 Q96RI1 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30787109 1.00 RAB9A (0.54) RAB9ANPC1KDM4EALDH1A1HPGD
SCHEMBL13998685 0.90 ALDH1A1 (0.59) RAB9ANPC1KDM4EALDH1A1HPGD
SCHEMBL13998715 0.86 HPGD (0.57) RAB9ANPC1KDM4EALDH1A1HPGD
SCHEMBL12910410 0.85 HPGD (0.56) RAB9ANPC1KDM4EALDH1A1HPGD
SCHEMBL9867688 0.84 SGMS2 (0.55) RAB9ANPC1KDM4EALDH1A1HPGD
SCHEMBL24454863 0.83 RAB9A (0.58) RAB9ANPC1KDM4EALDH1A1HPGD
SCHEMBL2244448 0.83 NPC1 (0.58) RAB9ANPC1KDM4EALDH1A1HPGD
SCHEMBL29686704 0.83 RAB9A (0.58) RAB9ANPC1KDM4EALDH1A1HPGD
SCHEMBL9868635 0.83 HPGD (0.54) RAB9ANPC1KDM4EALDH1A1HPGD
SCHEMBL23458473 0.83 ALDH1A1 (0.53) RAB9ANPC1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117279921-B Amine compound having azabenzoxazole ring structure and organic electroluminescent element using same 保土谷化学工业株式会社 2026-05-22 CN disclosed
WO-2025084253-A1 CARBAZOLE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2025-04-24 WO disclosed
US-20250109145-A1 ORGANIC ELECTROLUMINESCENT DEVICE, AND COMPOUND FOR THE SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2025-04-03 US disclosed
WO-2024218664-A1 CARBAZOLE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT 호도가야 가가쿠 고교 가부시키가이샤 2024-10-24 WO disclosed
EP-4389753-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOUND FOR SAME Hodogaya Chemical Co., Ltd. (JP) 2024-06-26 EP disclosed
EP-4389753-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOUND FOR SAME Hodogaya Chemical Co., Ltd. (JP) 2024-06-26 EP disclosed
CN-117279921-A Amine compound having azabenzoxazole ring structure and organic electroluminescent element using same 保土谷化学工业株式会社 2023-12-22 CN disclosed
WO-2023022186-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOUND FOR SAME 保土谷化学工業株式会社 2023-02-23 WO disclosed
WO-2022264974-A1 AMINE COMPOUND HAVING AZABENZOXAZOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 保土谷化学工業株式会社 2022-12-22 WO disclosed
US-20200203630-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2020-06-25 US disclosed
US-20090136448-A1 Antiviral 2-Carboxy-Thiophene Compounds CORFIELD JOHN ANDREW 2009-05-28 US disclosed
US-20090136448-A1 Antiviral 2-Carboxy-Thiophene Compounds CORFIELD JOHN ANDREW 2009-05-28 US disclosed
US-20090136448-A1 Antiviral 2-Carboxy-Thiophene Compounds CORFIELD JOHN ANDREW 2009-05-28 US disclosed
EP-1971599-A1 ANTIVIRAL 2-CARBOXY-THIOPHENE COMPOUNDS SmithKline Beecham Corporation (US) 2008-09-24 EP disclosed
WO-2007071434-A1 ANTIVIRAL 2-CARBOXY-THIOPHENE COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2007-06-28 WO disclosed
WO-2007071434-A1 ANTIVIRAL 2-CARBOXY-THIOPHENE COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090136448-A1 Antiviral 2-Carboxy-Thiophene Compounds EIF2AK2, HAVCR2, MAVS RAB9A 1920/4885NPC1 1833/4885KDM4E 794/4885
US-20250109145-A1 ORGANIC ELECTROLUMINESCENT DEVICE, AND COMPOUND FOR THE SAME TYR, AZI2, AOC1 RAB9A 3325/4885NPC1 2961/4885KDM4E 107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.