Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869785 | 0.85 | TUBB4A (0.45) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9869878 | 0.78 | KDM4E (0.44) | MAPTKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL9870091 | 0.77 | KDM4E (0.55) | MAPTKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL11009148 | 0.77 | BACE1 (0.49) | MAPTKDM4EALDH1A1HPGDKDR | |
| SCHEMBL11009952 | 0.73 | CYP2A6 (0.46) | MAPTKDM4EALDH1A1KMT2AKDR | |
| SCHEMBL9870239 | 0.71 | KDM4E (0.43) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL9329531 | 0.71 | PDE2A (0.37) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL14164494 | 0.69 | PDE5A (0.46) | MAPTKDM4EALDH1A1FYNRAB9A | |
| SCHEMBL19668723 | 0.69 | MAPT (0.47) | MAPTALDH1A1TDP2FYNRAB9A | |
| SCHEMBL28050431 | 0.69 | LRRK2 (0.51) | MAPTKDM4EALDH1A1HPGDTDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037980-A | Anxiolytic agents, hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1991-08-06 | — | — | US | claimed |
| US-5037980-A | Anxiolytic agents, hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1991-08-06 | — | — | US | disclosed |