Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 3/20 | 0.38 |
| ▸ | GABRD | O14764 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.38 |
| ▸ | GABRE | P78334 | 3/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316235 | 0.81 | POLB (0.39) | POLBTDP1L3MBTL1GABRPGABRD | |
| SCHEMBL9869186 | 0.77 | CA12 (0.42) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL6840685 | 0.75 | HCAR2 (0.44) | POLBTDP1L3MBTL1GABRPGABRD | |
| SCHEMBL9869319 | 0.70 | POLB (0.41) | POLBTDP1L3MBTL1GABRPGABRD | |
| SCHEMBL9869975 | 0.70 | GABRP (0.37) | POLBL3MBTL1GABRPGABRDGABRA1 | |
| SCHEMBL14900060 | 0.70 | TDP1 (0.46) | POLBTDP1L3MBTL1GABRPGABRD | |
| SCHEMBL2338977 | 0.69 | KDM5A (0.40) | POLBTDP1L3MBTL1GABRPGABRD | |
| SCHEMBL9317179 | 0.68 | MEN1 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL258457 | 0.68 | ALDH1A1 (0.43) | L3MBTL1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4116012 | 0.68 | GABRP (0.50) | TDP1GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997947-A | Forming 6-substituted pyridine-2,3-dicarboxylic esters followed by reacting with aminoalkanecarboxylic acid amide; herbicides, plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |