SCHEMBL9869186

SCHEMBL9869186

CCOC(=O)c1cc(CC)c(COC)nc1C(=O)OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA7 P43166 3/20 0.42
CA9 Q16790 3/20 0.42
CA14 Q9ULX7 3/20 0.42
ALOX15 P16050 1/20 0.42
KDM4E B2RXH2 3/20 0.41
TSHR P16473 2/20 0.41
ALDH1A1 P00352 3/20 0.40
HPGD P15428 1/20 0.40
GAA P10253 1/20 0.39
MAPK1 P28482 1/20 0.39
HSP90AA1 P07900 1/20 0.39
HSD17B10 Q99714 1/20 0.39
DPP4 P27487 2/20 0.39
KMT2A Q03164 1/20 0.39
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9869495 0.88 CA12 (0.42) CA12CA1CA2CA7CA9
SCHEMBL9315811 0.85 ALOX15 (0.45) CA12CA1CA2CA7CA9
SCHEMBL9869357 0.77 POLB (0.42) KDM4ETSHRALDH1A1HPGDHSD17B10
SCHEMBL8209732 0.75 KDM4E (0.56) ALOX15KDM4ETSHRALDH1A1HPGD
SCHEMBL29329021 0.75 KMT2A (0.50) KDM4ETSHRALDH1A1MAPK1HSP90AA1
SCHEMBL9869213 0.75 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL9868771 0.74 DHODH (0.41) CA12CA1CA2CA7CA9
SCHEMBL5846548 0.73 GABRA1 (0.46) CA12CA1CA2CA7CA9
SCHEMBL30968739 0.73 GABRA1 (0.46) CA12CA1CA2CA7CA9
SCHEMBL9800425 0.73 KDM4E (0.50) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5077127-A Glass or synthetic organic fibers; latex of highly saturated nitrile rubber; a resorcinol-formaldehyde resin; heat resistant; belts, hoses, diaphragms NIPPON ZEON CO., LTD. (JP) 1991-12-31 US disclosed
US-4997947-A Forming 6-substituted pyridine-2,3-dicarboxylic esters followed by reacting with aminoalkanecarboxylic acid amide; herbicides, plant growth regulators CIBA-GEIGY CORPORATION (US) 1991-03-05 US disclosed