Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258223 | 0.82 | ALDH1A1 (0.55) | L3MBTL1RAB9ATSHRALDH1A1CYP2C9 | |
| SCHEMBL158842 | 0.82 | POLB (0.49) | L3MBTL1RAB9ATSHRCASP3SENP8 | |
| SCHEMBL2306128 | 0.80 | SYK (0.48) | RAB9AALDH1A1CYP2C9SMN1; SMN2NPC1 | |
| SCHEMBL9869486 | 0.80 | POLB (0.47) | L3MBTL1RAB9ATSHRCASP3SENP8 | |
| SCHEMBL4500023 | 0.79 | L3MBTL1 (0.60) | L3MBTL1RAB9ATSHRCASP3SENP8 | |
| SCHEMBL6069713 | 0.78 | POLB (0.43) | L3MBTL1RAB9ATSHRCASP3SENP8 | |
| SCHEMBL4489937 | 0.77 | P2RX7 (0.55) | L3MBTL1RAB9AALDH1A1CYP2C9SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11508163 | 0.77 | SYK (0.46) | RAB9AALDH1A1CYP2C9SMN1; SMN2NPC1 | |
| SCHEMBL7109226 | 0.77 | TSHR (0.50) | L3MBTL1TSHRALDH1A1POLBLMNA | |
| SCHEMBL17595922 | 0.77 | L3MBTL1 (0.58) | L3MBTL1RAB9ATSHRCASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006532-A | Enzyme inhibitor; antiinflammatory agents | MERCK & CO. INC., INC. (US) | 1991-04-09 | — | — | US | disclosed |
| US-4904672-A | Derivatives of 3-hydroxyazabenzo[b]thiophene useful as 5-lipoxygenase inhibitors | MERCK & CO., INC. (US) | 1990-02-27 | — | — | US | disclosed |
| US-4767766-A | Derivatives of 3-hydroxyazabenzo(B)thiophene useful as 5-lipoxygenase inhibitors | MERCK & CO., INC. (US) | 1988-08-30 | — | — | US | disclosed |