Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869490 | 0.82 | KDM4E (0.45) | L3MBTL1PKMPOLBKDM4ETDP1 | |
| SCHEMBL4500023 | 0.82 | L3MBTL1 (0.60) | L3MBTL1PKMHSP90AA1POLBKDM4E | |
| SCHEMBL9661101 | 0.79 | L3MBTL1 (0.51) | L3MBTL1PKMPOLBTDP1RAB9A | |
| SCHEMBL971350 | 0.78 | L3MBTL1 (0.50) | L3MBTL1PKMHSP90AA1POLBKDM4E | |
| SCHEMBL9661187 | 0.76 | MAPT (0.48) | L3MBTL1PKMKDM4ETDP1RAB9A | |
| SCHEMBL158842 | 0.76 | POLB (0.49) | L3MBTL1PKMPOLBKDM4ETDP1 | |
| SCHEMBL7020791 | 0.76 | TSHR (0.49) | L3MBTL1PKMTDP1TSHRMAPT | |
| SCHEMBL258223 | 0.76 | ALDH1A1 (0.55) | L3MBTL1POLBKDM4ETDP1RAB9A | |
| SCHEMBL4489937 | 0.74 | P2RX7 (0.55) | L3MBTL1PKMPOLBKDM4ETDP1 | |
| SCHEMBL17595922 | 0.74 | L3MBTL1 (0.58) | L3MBTL1POLBKDM4ERAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5024923-A | Sulfur-containing metal complex | FUJI PHOTO FILM CO., LTD. (JP) | 1991-06-18 | — | — | US | disclosed |
| US-5006532-A | Enzyme inhibitor; antiinflammatory agents | MERCK & CO. INC., INC. (US) | 1991-04-09 | — | — | US | disclosed |
| US-4981773-A | Method for stabilization of organic base substances against light | FUJI PHOTO FILM CO., LTD. (JP) | 1991-01-01 | — | — | US | disclosed |
| US-4929540-A | 5-PYRAZOLONE COUPLER WITH NITROGEN-HETEROCYCLE-THIOELIMINATABLE GROUP | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-29 | — | — | US | disclosed |
| US-4904672-A | Derivatives of 3-hydroxyazabenzo[b]thiophene useful as 5-lipoxygenase inhibitors | MERCK & CO., INC. (US) | 1990-02-27 | — | — | US | disclosed |
| US-4767766-A | Derivatives of 3-hydroxyazabenzo(B)thiophene useful as 5-lipoxygenase inhibitors | MERCK & CO., INC. (US) | 1988-08-30 | — | — | US | disclosed |