Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1671165 | 0.82 | EPHX2 (0.56) | ALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL9164640 | 0.79 | EPHX2 (0.49) | KDM4EALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL4751222 | 0.79 | SMN1; SMN2 (0.58) | KDM4EALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL22904420 | 0.76 | GPR183 (0.52) | KDM4EALDH1A1SIGMAR1CXCR3MEN1 | |
| SCHEMBL5734193 | 0.72 | SIGMAR1 (0.68) | KDM4EALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL208118 | 0.72 | SIGMAR1 (0.68) | KDM4EALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL14025005 | 0.72 | LMNA (0.59) | KDM4EALDH1A1SIGMAR1CXCR3MEN1 | |
| Hydrochloric Acid SCHEMBL2921947 | 0.71 | CXCR4 (0.68) | KDM4EALDH1A1SIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4467874 | 0.71 | CXCR4 (0.68) | KDM4EALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL941871 | 0.71 | KDM4E (0.62) | KDM4EALDH1A1SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077288-A | Adrenergic, serotonin and histamine antagonist | ADIR ET COMPAGNIE (FR) | 1991-12-31 | — | — | US | disclosed |