Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | HTR2C | P28335 | 3/20 | 0.56 |
| ▸ | HTR7 | P34969 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10963542 | 0.94 | HTR2A (0.54) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL9870722 | 0.83 | DRD2 (0.52) | HTR2AHTR2CCYP2D6MEN1KMT2A | |
| SCHEMBL11014354 | 0.82 | HTR2A (0.60) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL9630285 | 0.81 | OPRM1 (0.44) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL11370701 | 0.81 | HTR2A (0.61) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL9870819 | 0.79 | KMT2A (0.51) | HTR2AHTR2CKDM4ECYP2D6ALDH1A1 | |
| SCHEMBL16466367 | 0.79 | HTR2A (0.59) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL10928975 | 0.78 | HTR2A (0.72) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL14318600 | 0.78 | HTR2A (0.81) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL14638486 | 0.78 | SMN1; SMN2 (0.62) | HTR2AHTR2CHTR7HTR6CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077288-A | Adrenergic, serotonin and histamine antagonist | ADIR ET COMPAGNIE (FR) | 1991-12-31 | — | — | US | disclosed |