Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25C | P30307 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9571788 | 0.73 | ALDH1A1 (0.52) | GPR3ALDH1A1TSHRKDM4ENQO2 | |
| SCHEMBL9870903 | 0.71 | ALDH1A1 (0.47) | GPR3ALDH1A1TSHRKDM4ENQO2 | |
| Hydrochloric Acid SCHEMBL9870422 | 0.70 | PAX8 (0.35) | GPR3KDM4ENQO2ATMERCC1 | |
| SCHEMBL19038517 | 0.69 | KCNH2 (0.45) | GPR3KDM4ENQO2ATMERCC1 | |
| SCHEMBL984 | 0.65 | HTR2A (0.54) | GPR3ALDH1A1TSHRKDM4ENQO2 | |
| SCHEMBL26168148 | 0.64 | GPR3 (0.45) | GPR3ALDH1A1TSHRKDM4ENQO2 | |
| SCHEMBL13157508 | 0.64 | KCNH2 (0.55) | KDM4EHSD17B10KCNH2 | |
| SCHEMBL1146660 | 0.63 | HTR2A (0.51) | GPR3ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL7428637 | 0.63 | HTR2A (0.51) | GPR3ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL30223533 | 0.63 | HTR2A (0.51) | GPR3ALDH1A1TSHRKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030646-A | Treatment of diseases resulting from disfunction of seretoninergic system | ADIR ET COMPAGNIE (FR) | 1991-07-09 | — | — | US | disclosed |