Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871045 | 0.81 | MEN1 (0.40) | MAPTNPC1RAB9AHTTCYP3A4 | |
| SCHEMBL9870757 | 0.76 | LMNA (0.41) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11418783 | 0.72 | MAPT (0.43) | NQO1LTA4HMAPTNPC1RAB9A | |
| SCHEMBL11880911 | 0.72 | NQO1 (0.52) | NQO1LTA4HMAPTALDH1A1 | |
| SCHEMBL8944052 | 0.67 | LTA4H (0.63) | NQO1LTA4HMAPTNPC1RAB9A | |
| SCHEMBL6306948 | 0.67 | LTA4H (0.63) | NQO1LTA4HMAPTNPC1RAB9A | |
| SCHEMBL2094646 | 0.67 | ALDH1A1 (0.46) | MAPTNPC1RAB9AHTTCYP1A2 | |
| SCHEMBL11777720 | 0.67 | NPC1 (0.48) | NQO1LTA4HMAPTNPC1RAB9A | |
| SCHEMBL9872013 | 0.66 | NQO1 (0.54) | NQO1LTA4HMAPTNPC1RAB9A | |
| SCHEMBL3239122 | 0.66 | NQO1 (0.74) | NQO1LTA4HMAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |