Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537235 | 0.86 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1CNR2MEN1KMT2A | |
| SCHEMBL9871685 | 0.80 | NPC1 (0.49) | ALDH1A1MAPTPOLBL3MBTL1CNR2 | |
| SCHEMBL9871105 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBTDP1L3MBTL1 | |
| SCHEMBL9871630 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBTDP1L3MBTL1 | |
| SCHEMBL10658030 | 0.74 | THRB (0.43) | ALDH1A1MAPTCNR2MEN1KMT2A | |
| SCHEMBL9873752 | 0.73 | FAAH (0.50) | ALDH1A1MAPTPOLBTDP1L3MBTL1 | |
| SCHEMBL9870759 | 0.73 | MGLL (0.47) | ALDH1A1MAPTKMT2ATSHRLMNA | |
| Diethylaniline SCHEMBL5585967 | 0.72 | TSHR (0.67) | ALDH1A1MAPTTDP1L3MBTL1CNR2 | |
| SCHEMBL3686969 | 0.71 | CNR2 (0.71) | ALDH1A1TDP1L3MBTL1CNR2MEN1 | |
| SCHEMBL81937 | 0.71 | CNR2 (0.71) | ALDH1A1TDP1L3MBTL1CNR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |