Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537235 | 0.82 | ALDH1A1 (0.58) | SMN1; SMN2CNR2LMNANPSR1L3MBTL1 | |
| SCHEMBL9871052 | 0.80 | ALDH1A1 (0.53) | NPC1RAB9AHPGDPOLBMAPT | |
| SCHEMBL9872013 | 0.77 | NQO1 (0.54) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL10345925 | 0.75 | NPC1 (0.54) | NPC1RAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL8387473 | 0.73 | ALOX5 (0.74) | ALOX5LTB4RLTB4R2 | |
| SCHEMBL29456812 | 0.73 | LTA4H (0.52) | NPC1RAB9ASMN1; SMN2MAPTCNR2 | |
| SCHEMBL9871903 | 0.73 | ALDH1A1 (0.52) | SMN1; SMN2POLBMAPTLMNALTA4H | |
| SCHEMBL8137171 | 0.73 | ALOX5 (0.64) | ALOX5LMNACYP1A2CYP2C19LTB4R | |
| SCHEMBL9806097 | 0.72 | LTA4H (0.59) | NPC1RAB9AHPGDSMN1; SMN2POLB | |
| SCHEMBL9871246 | 0.72 | MAPT (0.51) | HPGDSMN1; SMN2POLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |