Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | CTSV | O60911 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872949 | 0.91 | POLB (0.54) | ALDH1A1KDM4EHPGDPOLBDRD2 | |
| SCHEMBL9872909 | 0.79 | DRD2 (0.46) | DRD2DRD4DRD3KCNH2 | |
| SCHEMBL7797930 | 0.76 | MRGPRX4 (0.61) | ALDH1A1KDM4EHPGDMRGPRX4CTSV | |
| SCHEMBL7268160 | 0.75 | SLC16A3 (0.41) | ALDH1A1KDM4EHPGDPOLBMRGPRX4 | |
| SCHEMBL21327232 | 0.74 | MRGPRX4 (0.61) | ALDH1A1KDM4EHPGDMRGPRX4CTSV | |
| SCHEMBL9524235 | 0.73 | CYP19A1 (0.48) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL3655431 | 0.71 | KDM4E (0.49) | ALDH1A1KDM4EHPGDMRGPRX4MEN1 | |
| SCHEMBL8711005 | 0.71 | POLB (0.60) | ALDH1A1KDM4EPOLBDRD4DRD3 | |
| SCHEMBL11463716 | 0.70 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDMRGPRX4DRD2 | |
| SCHEMBL6844761 | 0.69 | POLB (0.58) | ALDH1A1KDM4EHPGDPOLBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017582-A | Analgesics | SANDOZ LTD. (CH) | 1991-05-21 | — | — | US | disclosed |
| US-4910207-A | Antipsychotic agent | NOVARTIS AG (CH) | 1990-03-20 | — | — | US | disclosed |
| US-4803199-A | SEROTONIN ANTAGONIST, ANALGESIC ANTIARRHYTHMIC AGENTS | NOVARTIS AG (CH) | 1989-02-07 | — | — | US | disclosed |