Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872858 | 0.81 | DRD2 (0.67) | DRD2KCNH2OPRK1HTR3ADRD4 | |
| SCHEMBL9872863 | 0.81 | DRD2 (0.67) | DRD2KCNH2OPRK1HTR3ADRD4 | |
| SCHEMBL9872949 | 0.81 | POLB (0.54) | DRD2DRD4DRD3 | |
| SCHEMBL9872897 | 0.79 | POLB (0.49) | DRD2KCNH2DRD4DRD3 | |
| SCHEMBL9872901 | 0.79 | POLB (0.49) | DRD2KCNH2DRD4DRD3 | |
| SCHEMBL9871670 | 0.79 | ALDH1A1 (0.44) | DRD2KCNH2DRD4DRD3 | |
| SCHEMBL10517083 | 0.67 | KCNH2 (0.61) | KCNH2OPRK1OPRM1CHRNA7 | |
| SCHEMBL10517086 | 0.67 | KCNH2 (0.61) | KCNH2OPRK1OPRM1CHRNA7 | |
| Hydrochloric Acid SCHEMBL9384270 | 0.66 | KCNH2 (0.60) | KCNH2OPRK1OPRM1CHRNA7 | |
| Hydrochloric Acid SCHEMBL9384273 | 0.66 | KCNH2 (0.60) | KCNH2OPRK1OPRM1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017582-A | Analgesics | SANDOZ LTD. (CH) | 1991-05-21 | — | — | US | disclosed |
| US-4910207-A | Antipsychotic agent | NOVARTIS AG (CH) | 1990-03-20 | — | — | US | disclosed |
| US-4803199-A | SEROTONIN ANTAGONIST, ANALGESIC ANTIARRHYTHMIC AGENTS | NOVARTIS AG (CH) | 1989-02-07 | — | — | US | disclosed |