Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871670 | 0.91 | ALDH1A1 (0.44) | POLBKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL9872909 | 0.81 | DRD2 (0.46) | DRD2DRD4DRD3 | |
| SCHEMBL21327080 | 0.75 | POLB (0.58) | POLBKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL8882626 | 0.74 | CA12 (0.48) | KDM4EMEN1KMT2AGAALMNA | |
| SCHEMBL9872943 | 0.73 | POLB (0.71) | POLBKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL21327265 | 0.72 | ALDH1A1 (0.56) | POLBKDM4ELMNAHPGDNPC1 | |
| SCHEMBL9524235 | 0.72 | CYP19A1 (0.48) | KDM4EMEN1KMT2AGAAMAPT | |
| SCHEMBL7268160 | 0.69 | SLC16A3 (0.41) | POLBKDM4EMEN1KMT2AHPGD | |
| SCHEMBL7419408 | 0.69 | GAA (0.74) | POLBKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL1019564 | 0.68 | HPGD (0.49) | POLBKDM4EGAALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017582-A | Analgesics | SANDOZ LTD. (CH) | 1991-05-21 | — | — | US | disclosed |
| US-4910207-A | Antipsychotic agent | NOVARTIS AG (CH) | 1990-03-20 | — | — | US | disclosed |
| US-4803199-A | SEROTONIN ANTAGONIST, ANALGESIC ANTIARRHYTHMIC AGENTS | NOVARTIS AG (CH) | 1989-02-07 | — | — | US | disclosed |