Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871903 | 0.84 | ALDH1A1 (0.52) | NQO1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL9871246 | 0.82 | MAPT (0.51) | NQO1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL3832407 | 0.79 | ALDH1A1 (0.77) | NQO1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL8006543 | 0.78 | PARP10 (0.58) | NQO1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL9871685 | 0.77 | NPC1 (0.49) | ALDH1A1MAPTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL13316967 | 0.77 | NQO1 (0.67) | NQO1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL60209 | 0.77 | NQO1 (0.67) | NQO1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL3239122 | 0.77 | NQO1 (0.74) | NQO1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL11880911 | 0.76 | NQO1 (0.52) | NQO1ALDH1A1MAPTGAALTA4H | |
| SCHEMBL881180 | 0.75 | NQO1 (0.64) | NQO1ALDH1A1MAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |