Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SOD1 | P00441 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 5/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.32 |
| ▸ | S100A9 | P06702 | 2/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655158 | 0.96 | F2 (0.31) | SOD1CYP3A4ALDH1A1F2PRSS1 | |
| SCHEMBL8854126 | 0.80 | PGR (0.45) | ALDH1A1PGR | |
| SCHEMBL1125078 | 0.78 | F2 (0.52) | CYP3A4ALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL5653955 | 0.74 | F2 (0.37) | CYP3A4CYP2D6ALDH1A1F2PRSS1 | |
| SCHEMBL5654748 | 0.74 | MAPK1 (0.46) | FLT1FLT4KDRALDH1A1F2 | |
| SCHEMBL5652655 | 0.71 | CA2 (0.44) | TSHRALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL5652756 | 0.71 | F2 (0.36) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL5655635 | 0.70 | TDP1 (0.38) | CYP3A4ALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL9869981 | 0.69 | KMT2A (0.42) | CA1CA2CA9 | |
| SCHEMBL10871074 | 0.69 | TRPV4 (0.37) | TSHRCYP3A4ALDH1A1F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996208-A | Pesticidal thiazolopyrimidine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-26 | — | — | US | disclosed |
| EP-0348746-A2 | Thiazolopyrimidine derivatives, process for their preparation and their use as pest control agents | BAYER AG (DE) | 1990-01-03 | — | — | EP | disclosed |