SCHEMBL746177

SCHEMBL746177

COc1cc(C(=O)O)nc(C(=O)O)c1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.55
LMNA P02545 1/20 0.55
ALOX15 P16050 3/20 0.54
TSHR P16473 2/20 0.54
HIF1A Q16665 1/20 0.54
GPR35 Q9HC97 1/20 0.49
MCL1 Q07820 3/20 0.47
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
MAPT P10636 1/20 0.47
RECQL P46063 1/20 0.47
KDM4E B2RXH2 3/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
RXRA P19793 1/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
ACMSD Q8TDX5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL794917 0.98 TDP1 (0.53) TDP1LMNAALOX15TSHRHIF1A
SCHEMBL27730282 0.90 LMNA (0.47) TDP1LMNAALOX15TSHRHIF1A
SCHEMBL987189 0.88 TDP1 (0.62) TDP1LMNAALOX15TSHRHIF1A
SCHEMBL7226501 0.88 KDM4E (0.53) TDP1LMNAALOX15TSHRHIF1A
SCHEMBL6742246 0.86 LMNA (0.47) TDP1LMNAALOX15TSHRHIF1A
SCHEMBL1424822 0.86 LMNA (0.47) TDP1LMNAALOX15TSHRHIF1A
SCHEMBL29503803 0.86 LMNA (0.47) TDP1LMNAALOX15TSHRHIF1A
SCHEMBL1424927 0.86 LMNA (0.51) TDP1LMNAALOX15TSHRHIF1A
SCHEMBL27537190 0.83 LMNA (0.45) TDP1LMNAALOX15TSHRHIF1A
SCHEMBL28466289 0.82 CYP3A4 (0.46) ALDH1A1HPGDMAPTRECQLKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504867-A Pyridine dicarboxylic acid coordinated catalyst, composite catalyst, preparation method and application 上海元革新材料科技有限公司 2025-02-25 CN claimed
CN-118878806-B Zinc pyridine carboxylate complex composite catalyst and preparation method thereof 安徽普碳新材料科技有限公司 2025-02-21 CN claimed
CN-118878806-A Zinc pyridine carboxylate complex composite catalyst and preparation method thereof 安徽普碳新材料科技有限公司 2024-11-01 CN claimed
CN-119504867-A Pyridine dicarboxylic acid coordinated catalyst, composite catalyst, preparation method and application 上海元革新材料科技有限公司 2025-02-25 CN disclosed
CN-118878806-B Zinc pyridine carboxylate complex composite catalyst and preparation method thereof 安徽普碳新材料科技有限公司 2025-02-21 CN disclosed
CN-118878808-B Composite catalyst containing zinc pyridine carboxylate complex and preparation method and application thereof 合肥普力先进材料科技有限公司 2024-12-24 CN disclosed
CN-118878808-A Composite catalyst containing zinc pyridine carboxylate complex and preparation method and application thereof 合肥普力先进材料科技有限公司 2024-11-01 CN disclosed
CN-118878806-A Zinc pyridine carboxylate complex composite catalyst and preparation method thereof 安徽普碳新材料科技有限公司 2024-11-01 CN disclosed
US-11760701-B2 Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YROK (US) 2023-09-19 US disclosed
US-20210221784-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PAIN UNIVERSITÉ DE STRASBOURG (FR) 2021-07-22 US disclosed
US-20210032181-A1 DIFLUOROMETHOXYLATION AND TRIFLUOROMETHOXYLATION COMPOSITIONS AND METHODS FOR SYNTHESIZING SAME THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2021-02-04 US disclosed
US-20100280002-A1 AMINOPYRIDINE-DERIVATIVES AS INDUCTIBLE NO-SYNTHASE INHIBITORS ALTANA PHARMA AG (DE) 2010-11-04 US disclosed
US-7781453-B2 Aminopyridine-derivatives ALTANA PHARMA AG (DE) 2010-08-24 US disclosed
US-20080176894-A1 Used as nitric oxide synthase inhibitors; treating acute inflammatory disease with such as 2-[2-(2-amino-4-methylpyridin-6-yl)ethyl]-3H-imidazo[4,5-b]pyridine ALTANA PHARMA AG 2008-07-24 US disclosed
US-7317021-B2 Aminopyridine-derivatives as inductible no-synthase inhibitors ALTANA PHARMA AG (DE) 2008-01-08 US disclosed
US-20070043072-A1 Aminopyridine-derivatives as inductible no-synthase inhibitors ALTANA PHARMA AG (DE) 2007-02-22 US disclosed
EP-1670798-A1 AMINOPYRIDINE-DERIVATIVES AS INDUCTIBLE NO-SYNTHASE INHIBITORS Altana Pharma AG (DE) 2006-06-21 EP disclosed
WO-2005061496-A1 AMINOPYRIDINE-DERIVATIVES AS INDUCTIBLE NO-SYNTHASE INHIBITORS ALTANA PHARMA AG (DE) 2005-07-07 WO disclosed
EP-0871065-B1 Method for processing a silver halide color photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 2002-08-28 EP disclosed
EP-0871065-A1 Method for processing a silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1998-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210221784-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PAIN ACHE, TRPV1, OPRL1 TDP1 3054/4885LMNA 3480/4885ALOX15 137/4885
US-20070043072-A1 Aminopyridine-derivatives as inductible no-synthase inhibitors NOS2, NOS1, NOS3 TDP1 620/4885LMNA 4640/4885ALOX15 1504/4885
US-20100280002-A1 AMINOPYRIDINE-DERIVATIVES AS INDUCTIBLE NO-SYNTHASE INHIBITORS NOS2, NOS1, NOS3 TDP1 620/4885LMNA 4640/4885ALOX15 1504/4885
US-20080176894-A1 Used as nitric oxide synthase inhibitors; treating acute inflammatory disease with such as 2-[2-(2-amino-4-methylpyridin-6-yl)ethyl]-3H-imidazo[4,5-b]pyridine NOS2, NOS1, NOS3 TDP1 1471/4885LMNA 4337/4885ALOX15 287/4885
US-20210032181-A1 DIFLUOROMETHOXYLATION AND TRIFLUOROMETHOXYLATION COMPOSITIONS AND METHODS FOR SYNTHESIZING SAME AFF2, AFF4, AFF1 TDP1 2207/4885LMNA 2457/4885ALOX15 3276/4885
US-11760701-B2 Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same AFF2, AFF4, AFF1 TDP1 2207/4885LMNA 2457/4885ALOX15 3276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.