Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872218 | 0.92 | ESR1 (0.55) | ALDH1A1TSHRESR1LMNAMAPT | |
| SCHEMBL124262 | 0.89 | CA12 (0.50) | ALDH1A1TSHRESR1LMNAMAPT | |
| SCHEMBL9872852 | 0.89 | TSHR (0.37) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| SCHEMBL9873018 | 0.88 | TSHR (0.42) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| SCHEMBL9871106 | 0.82 | ESR1 (0.57) | ALDH1A1TSHRESR1TDP1SLC6A2 | |
| SCHEMBL7746430 | 0.81 | MAPT (0.47) | ALDH1A1TSHRTDP1LMNAMAPT | |
| SCHEMBL9873068 | 0.81 | RAB9A (0.47) | ALDH1A1TSHRESR1TDP1LMNA | |
| SCHEMBL13873051 | 0.81 | TDP1 (0.40) | ALDH1A1TSHRESR1TDP1LMNA | |
| SCHEMBL9874221 | 0.81 | CA12 (0.49) | TSHRLMNAMAPTRAB9ANPC1 | |
| SCHEMBL9872599 | 0.80 | APP (0.50) | ESR1TDP1LMNASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064959-A | Photoinitiators | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-12 | — | — | US | disclosed |