Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872065 | 0.88 | ALDH1A1 (0.53) | TSHRCYP3A4ESR1ALDH1A1CHRM1 | |
| SCHEMBL9872852 | 0.87 | TSHR (0.37) | TSHRCYP3A4ESR1ALDH1A1CHRM1 | |
| SCHEMBL9872218 | 0.85 | ESR1 (0.55) | TSHRCYP3A4ESR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL124262 | 0.85 | CA12 (0.50) | TSHRCYP3A4ESR1ALDH1A1CA1 | |
| SCHEMBL9871106 | 0.83 | ESR1 (0.57) | TSHRCYP3A4ESR1ALDH1A1SLC6A2 | |
| SCHEMBL7746430 | 0.83 | MAPT (0.47) | TSHRALDH1A1TDP1CA1CA2 | |
| SCHEMBL9873068 | 0.82 | RAB9A (0.47) | TSHRESR1ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL13873051 | 0.80 | TDP1 (0.40) | TSHRCYP3A4ESR1ALDH1A1TDP1 | |
| SCHEMBL9874221 | 0.80 | CA12 (0.49) | TSHRCA1CA2MAPTNPC1 | |
| SCHEMBL9969969 | 0.77 | TSHR (0.64) | TSHRCYP3A4ABCB11ADRA2BOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064959-A | Photoinitiators | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-12 | — | — | US | disclosed |