Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872065 | 0.89 | ALDH1A1 (0.53) | TSHRESR1TDP1ALDH1A1CHRM1 | |
| SCHEMBL9873018 | 0.87 | TSHR (0.42) | TSHRESR1TDP1ALDH1A1CHRM1 | |
| SCHEMBL9872218 | 0.86 | ESR1 (0.55) | TSHRESR1ALDH1A1LMNACYP1A2 | |
| SCHEMBL124262 | 0.85 | CA12 (0.50) | TSHRESR1ALDH1A1LMNACYP1A2 | |
| SCHEMBL9871106 | 0.84 | ESR1 (0.57) | TSHRESR1TDP1ALDH1A1SLC6A2 | |
| SCHEMBL13873051 | 0.83 | TDP1 (0.40) | TSHRESR1TDP1ALDH1A1LMNA | |
| SCHEMBL9873068 | 0.83 | RAB9A (0.47) | TSHRESR1TDP1ALDH1A1LMNA | |
| SCHEMBL9874221 | 0.83 | CA12 (0.49) | TSHRLMNAMAPTKDM4EMEN1 | |
| SCHEMBL7746430 | 0.80 | MAPT (0.47) | TSHRTDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13528086 | 0.79 | PTGER4 (0.46) | CYP1A2CYP2C19CYP2D6CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064959-A | Photoinitiators | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-12 | — | — | US | disclosed |