Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825553 | 0.89 | ALDH1A1 (0.50) | SLC6A2SLC6A4NOS1ALDH1A1TSHR | |
| SCHEMBL241880 | 0.84 | CYP4F2 (0.53) | NOS1CYP4F2CYP4A11TBXA2RTAAR1 | |
| SCHEMBL19497012 | 0.84 | TAAR1 (0.53) | SLC6A2SLC6A4NOS1TAAR1HTR7 | |
| SCHEMBL989636 | 0.82 | ALDH1A1 (0.67) | NOS1ALDH1A1TSHRGRIN2DGRIN3B | |
| SCHEMBL2646040 | 0.80 | ALDH1A1 (0.54) | NOS1ALDH1A1TSHRHTR7 | |
| SCHEMBL9872968 | 0.80 | MAOA (0.52) | NOS1ALDH1A1TSHRGRIN2DGRIN3B | |
| SCHEMBL10750679 | 0.80 | NOS1 (0.50) | NOS1ALDH1A1TSHRGRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL8076952 | 0.79 | LPL (0.53) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL28919564 | 0.79 | LPL (0.53) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL8494349 | 0.79 | ALDH1A1 (0.52) | NOS1ALDH1A1TSHRGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021429-A | Histamine h2-antagonists; antisecretory-antiallergen agent; skin disorders and peptic ulcers | ALLEN & HANSBURYS LIMITED (GB) | 1991-06-04 | — | — | US | disclosed |
| EP-0029306-B1 | AMINOALKYL COMPOUNDS, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1984-07-25 | — | — | EP | disclosed |
| EP-0029306-A1 | Aminoalkyl compounds, their production and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1981-05-27 | — | — | EP | disclosed |