Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.30 |
| ▸ | RELA | Q04206 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873250 | 0.77 | SYK (0.64) | SYKRAB9ATP53SMN1; SMN2HTT | |
| SCHEMBL9873609 | 0.74 | FLT1 (0.38) | SYKF10HRH4MEN1KMT2A | |
| SCHEMBL17543219 | 0.73 | MRGPRX4 (0.47) | MRGPRX4 | |
| SCHEMBL810931 | 0.73 | MGAM (0.47) | NPC1RAB9AMRGPRX4NFKB1NFKB2 | |
| SCHEMBL31442635 | 0.73 | MGAM (0.47) | NPC1RAB9AMRGPRX4NFKB1NFKB2 | |
| SCHEMBL9879616 | 0.72 | PPOX (0.32) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL30729937 | 0.71 | SYK (0.64) | SYKRAB9ATP53SMN1; SMN2HTT | |
| SCHEMBL21835202 | 0.71 | SYK (0.64) | SYKRAB9ATP53SMN1; SMN2HTT | |
| SCHEMBL30946184 | 0.70 | LOXL2 (0.41) | SYK | |
| SCHEMBL8599602 | 0.70 | PPOX (0.45) | NPC1RAB9AMEN1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017213-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0351641-A1 | 1-Phenylpyrrole | NIHON BAYER AGROCHEM K.K. (JP) | 1990-01-24 | — | — | EP | disclosed |