Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SCN4A | P35499 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 7/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | HRH2 | P25021 | 4/20 | 0.47 |
| ▸ | HRH1 | P35367 | 3/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14370041 | 0.88 | SCN3A (0.52) | SCN3ASCN9ASCN5ALMNAPOLB | |
| SCHEMBL4425041 | 0.80 | DRD2 (0.52) | SCN3ASCN9ASCN5ALMNAPOLB | |
| Bromide SCHEMBL4429410 | 0.78 | DRD2 (0.51) | SCN3ASCN9ASCN5ALMNAPOLB | |
| SCHEMBL8280705 | 0.78 | DRD3 (0.58) | SCN3ASCN9ASCN5ALMNAPOLB | |
| SCHEMBL23201349 | 0.78 | SCN3A (0.62) | SCN3ASCN9ASCN5ASCN4ADRD2 | |
| SCHEMBL8296502 | 0.78 | DPP4 (0.47) | SCN3ASCN9ASCN5ASCN4ADRD2 | |
| SCHEMBL6866770 | 0.77 | DRD2 (0.50) | SCN3ASCN9ASCN5ALMNAPOLB | |
| SCHEMBL9873084 | 0.77 | PDK1 (0.66) | SCN3ASCN9ASCN5ALMNAPOLB | |
| Thiourea SCHEMBL6094460 | 0.77 | DRD2 (0.47) | SCN3ASCN9ASCN5ALMNAPOLB | |
| SCHEMBL9873864 | 0.76 | MASP2 (0.51) | SCN3ASCN9ASCN5ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |