Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PARG | Q86W56 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6020817 | 0.87 | TSHR (0.57) | ALDH1A1TP53GAAKMT2AMEN1 | |
| SCHEMBL9577200 | 0.87 | ALDH1A1 (0.68) | ALDH1A1TP53GAAKMT2AMEN1 | |
| SCHEMBL9869796 | 0.85 | GAA (0.54) | ALDH1A1GAAKMT2AMEN1PKM | |
| SCHEMBL9870435 | 0.84 | ALDH1A1 (0.74) | ALDH1A1TP53GAAKMT2AMEN1 | |
| SCHEMBL9870931 | 0.84 | FBP1 (0.52) | ALDH1A1TP53KMT2AMEN1PKM | |
| SCHEMBL11629929 | 0.80 | ALDH1A1 (0.59) | ALDH1A1TP53GAAKMT2AMEN1 | |
| SCHEMBL16541838 | 0.80 | KMT2A (0.59) | ALDH1A1TP53GAAKMT2AMEN1 | |
| SCHEMBL7613900 | 0.80 | TBXA2R (0.62) | ALDH1A1TP53GAAKMT2AMEN1 | |
| SCHEMBL7617764 | 0.80 | TSHR (0.59) | ALDH1A1TP53GAAKMT2AMEN1 | |
| SCHEMBL27278034 | 0.80 | MEN1 (0.59) | ALDH1A1TP53GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997847-A | Thromboxane A2 antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (DE) | 1991-03-05 | — | — | US | disclosed |
| EP-0304271-A2 | Omega-arylsulphonamidoalkanoic acids for treatment of thromboxane medited diseases | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-02-22 | — | — | EP | disclosed |