Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PARG | Q86W56 | 1/20 | 0.51 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872185 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL9870435 | 0.84 | ALDH1A1 (0.74) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL5505553 | 0.81 | FBP1 (0.59) | FBP1ALDH1A1KDM4ELMNAPKM | |
| SCHEMBL6689816 | 0.81 | PGR (0.51) | FBP1ALDH1A1LMNAPKMKMT2A | |
| SCHEMBL31014170 | 0.80 | LMNA (0.56) | FBP1ALDH1A1KDM4ELMNAPKM | |
| SCHEMBL9870700 | 0.78 | FABP4 (0.77) | FBP1ALDH1A1KDM4ELMNAPKM | |
| SCHEMBL9872117 | 0.78 | FABP4 (0.77) | FBP1ALDH1A1KDM4ELMNAPKM | |
| SCHEMBL9871347 | 0.78 | FABP4 (0.77) | FBP1ALDH1A1KDM4ELMNAPKM | |
| SCHEMBL1287335 | 0.76 | ALDH1A1 (0.72) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL9869796 | 0.75 | GAA (0.54) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997847-A | Thromboxane A2 antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (DE) | 1991-03-05 | — | — | US | disclosed |
| EP-0304271-A2 | Omega-arylsulphonamidoalkanoic acids for treatment of thromboxane medited diseases | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-02-22 | — | — | EP | disclosed |