Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872284 | 0.73 | RAB9A (0.46) | RAB9ANPC1MEN1KMT2ACYP1A2 | |
| SCHEMBL9874199 | 0.66 | KMT2A (0.62) | RAB9ANPC1MEN1KMT2ACYP1A2 | |
| SCHEMBL28704922 | 0.65 | RAB9A (0.88) | RAB9ANPC1MEN1KMT2ACYP1A2 | |
| SCHEMBL9874162 | 0.65 | CYP1A2 (0.49) | RAB9ANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9873702 | 0.64 | LMNA (0.45) | RAB9ANPC1MEN1KMT2ACYP1A2 | |
| SCHEMBL9114677 | 0.63 | RAB9A (0.52) | RAB9ANPC1MEN1KMT2ACYP1A2 | |
| SCHEMBL9113426 | 0.63 | LMNA (0.52) | — | |
| SCHEMBL9114789 | 0.63 | LMNA (0.52) | — | |
| SCHEMBL9873430 | 0.63 | LMNA (0.52) | — | |
| SCHEMBL9872933 | 0.63 | LMNA (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073565-A | Atherosclerosis, anticholesterol | WARNER-LAMBERT COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| WO-1991017150-A1 | TETRAZOLE UREA AND THIOUREA ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-11-14 | — | — | WO | disclosed |