Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874253 | 0.89 | RORC (0.43) | RORCCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL9872276 | 0.84 | RORC (0.41) | RORCCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL9873858 | 0.83 | RORC (0.42) | RORCCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL9874569 | 0.77 | RORC (0.41) | RORCCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL5097407 | 0.75 | MIF (0.49) | CTSLCTSBCTSSALDH1A1GAA | |
| SCHEMBL9875839 | 0.74 | RORC (0.40) | RORCCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL12133695 | 0.74 | SLC6A2 (0.45) | CTSLCTSBCTSSALDH1A1GAA | |
| SCHEMBL15873873 | 0.74 | CTSL (0.47) | CTSLCTSBCTSSMGLLLMNA | |
| Hydrochloric Acid SCHEMBL15873872 | 0.73 | CTSL (0.46) | CTSLCTSBCTSSLMNASMN1; SMN2 | |
| SCHEMBL2147161 | 0.72 | HTT (0.42) | RORCCTSLCTSBCTSSMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |