Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872800 | 0.89 | RORC (0.43) | RORCCTSLCTSBCTSSRAB9A | |
| SCHEMBL9872276 | 0.84 | RORC (0.41) | RORCCTSLCTSBCTSSMEN1 | |
| SCHEMBL9874569 | 0.78 | RORC (0.41) | RORCCTSLCTSBCTSSMEN1 | |
| SCHEMBL9873858 | 0.78 | RORC (0.42) | RORCCTSLCTSBCTSSRAB9A | |
| SCHEMBL17892948 | 0.73 | PKM (0.45) | CTSLCTSBCTSSKMT2ARAB9A | |
| SCHEMBL5097407 | 0.72 | MIF (0.49) | CTSLCTSBCTSSRAB9ANPC1 | |
| SCHEMBL15873873 | 0.72 | CTSL (0.47) | CTSLCTSBCTSSMGLLSMN1; SMN2 | |
| SCHEMBL31644614 | 0.72 | LMNA (0.58) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL14743992 | 0.71 | CTSL (0.54) | CTSLCTSBCTSSRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL15873872 | 0.71 | CTSL (0.46) | CTSLCTSBCTSSSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |