Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872800 | 0.84 | RORC (0.43) | RORCCTSLCTSBCTSSNPC1 | |
| SCHEMBL9874253 | 0.84 | RORC (0.43) | RORCCTSLCTSBCTSSNPC1 | |
| SCHEMBL9874569 | 0.78 | RORC (0.41) | RORCCTSLCTSBCTSSNPC1 | |
| SCHEMBL9875004 | 0.76 | RORC (0.36) | RORCCTSLCTSBCTSSL3MBTL1 | |
| SCHEMBL9873858 | 0.74 | RORC (0.42) | RORCCTSLCTSBCTSSNPC1 | |
| SCHEMBL19784031 | 0.74 | CTSS (0.52) | CTSLCTSBCTSSNPC1RAB9A | |
| SCHEMBL7012029 | 0.73 | TP53 (0.43) | PPIDL3MBTL1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL9261508 | 0.70 | MRGPRX4 (0.43) | NPC1RAB9ASMN1; SMN2TDP1KDM4E | |
| SCHEMBL16219332 | 0.70 | CTSL (0.52) | CTSLCTSBCTSSNPC1RAB9A | |
| SCHEMBL2913795 | 0.70 | CTSS (0.55) | CTSLCTSBCTSSNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |