Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310780 | 0.98 | TTR (0.50) | TTRENPP2CA1CA2EGFR | |
| SCHEMBL29465759 | 0.98 | TTR (0.50) | TTRENPP2CA1CA2EGFR | |
| SCHEMBL2407029 | 0.84 | TRPV6 (0.46) | TTRENPP2KMO | |
| SCHEMBL31333 | 0.80 | TTR (0.55) | TTRENPP2CA1CA2EGFR | |
| SCHEMBL128893 | 0.77 | ENPP2 (0.46) | TTRENPP2CA1CA2MGLL | |
| SCHEMBL130450 | 0.77 | TTR (0.61) | TTRENPP2CA1CA2TSHR | |
| SCHEMBL28490899 | 0.75 | ENPP2 (0.44) | TTRENPP2CA1CA2MGLL | |
| SCHEMBL9872902 | 0.74 | RAPGEF4 (0.33) | KMO | |
| SCHEMBL423468 | 0.73 | ENPP2 (0.44) | TTRENPP2CA1CA2MGLL | |
| SCHEMBL15646351 | 0.73 | CA2 (0.42) | TTRENPP2CA1CA2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009016-A2 | HALOPHENYL SUBSTITUTED HETEROCYCLIC DERIVATIVES | MERCK PATENT GMBH (DE) | 1991-06-27 | — | — | WO | disclosed |