Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 7/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872897 | 1.00 | POLB (0.49) | POLBDRD2DRD4SIGMAR1DRD3 | |
| SCHEMBL9872863 | 0.82 | DRD2 (0.67) | DRD2DRD4DRD3KCNH2 | |
| SCHEMBL9872858 | 0.82 | DRD2 (0.67) | DRD2DRD4DRD3KCNH2 | |
| SCHEMBL9872943 | 0.81 | POLB (0.71) | POLBDRD2DRD4DRD3 | |
| SCHEMBL9872909 | 0.79 | DRD2 (0.46) | DRD2DRD4DRD3KCNH2 | |
| SCHEMBL8711005 | 0.78 | POLB (0.60) | POLBDRD4DRD3KCNH2 | |
| SCHEMBL8708189 | 0.77 | POLB (0.57) | POLBDRD2DRD4DRD3 | |
| SCHEMBL11092131 | 0.72 | DRD4 (0.51) | DRD2DRD4DRD3 | |
| SCHEMBL3028929 | 0.72 | NPC1 (0.54) | POLB | |
| SCHEMBL11089665 | 0.71 | DRD4 (0.52) | POLBDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017582-A | Analgesics | SANDOZ LTD. (CH) | 1991-05-21 | — | — | US | disclosed |
| US-4910207-A | Antipsychotic agent | NOVARTIS AG (CH) | 1990-03-20 | — | — | US | disclosed |
| US-4803199-A | SEROTONIN ANTAGONIST, ANALGESIC ANTIARRHYTHMIC AGENTS | NOVARTIS AG (CH) | 1989-02-07 | — | — | US | disclosed |