Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.50 |
| ▸ | MAOA | P21397 | 9/20 | 0.50 |
| ▸ | KDM1A | O60341 | 6/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872861 | 0.78 | MAOB (0.45) | MAOBMAOAKDM1ALOXL2CYP2A6 | |
| SCHEMBL5282506 | 0.76 | MAOB (0.43) | MAOBMAOAKDM1ALOXL2CALM1 | |
| SCHEMBL5282094 | 0.73 | OPRL1 (0.42) | MAOBMAOAKDM1ALOXL2CALM1 | |
| SCHEMBL22032520 | 0.73 | MAOA (0.40) | MAOBMAOAKDM1ALOXL2CALM1 | |
| SCHEMBL9978691 | 0.73 | MAOB (0.40) | MAOBMAOAKDM1ALOXL2CALM1 | |
| SCHEMBL5278331 | 0.73 | MAOA (0.40) | MAOBMAOAKDM1ALOXL2CALM1 | |
| SCHEMBL5284942 | 0.73 | MAOA (0.40) | MAOBMAOAKDM1ALOXL2CALM1 | |
| SCHEMBL5277481 | 0.73 | ELANE (0.40) | MAOBMAOACALM1BACE1 | |
| SCHEMBL5274344 | 0.73 | MAOA (0.40) | MAOBMAOAKDM1ALOXL2CALM1 | |
| SCHEMBL3034490 | 0.73 | MAOA (0.40) | MAOBMAOAKDM1ALOXL2CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017150-A1 | TETRAZOLE UREA AND THIOUREA ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-11-14 | — | — | WO | disclosed |