Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29200269 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTTSHRL3MBTL1TDP1 | |
| SCHEMBL2721214 | 0.75 | MAPT (0.52) | ALDH1A1MAPTTSHRL3MBTL1TDP1 | |
| SCHEMBL11895737 | 0.73 | MAPT (0.48) | ALDH1A1MAPTTSHRL3MBTL1ALOX15 | |
| SCHEMBL4030091 | 0.73 | MAPT (0.64) | ALDH1A1MAPTTSHRL3MBTL1CYP1A2 | |
| SCHEMBL1185276 | 0.72 | MAPT (0.61) | ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL24881438 | 0.71 | MAPT (0.44) | ALDH1A1MAPTTSHRL3MBTL1TDP1 | |
| SCHEMBL3466699 | 0.71 | MAPT (0.44) | ALDH1A1MAPTTSHRL3MBTL1TDP1 | |
| SCHEMBL8756917 | 0.70 | — | — | |
| SCHEMBL21496091 | 0.70 | MAPT (0.43) | ALDH1A1MAPTTSHRL3MBTL1CA12 | |
| SCHEMBL27900277 | 0.70 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375527-A1 | N-aryl-azetidinones, process for their preparation and their use as elastase inhibitors | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1990-06-27 | — | — | EP | claimed |
| US-5030628-A | Leukocytic and pancreatic; for respiratory system disorders, antiarthritic, antiinflammatory, aging resistance | SCIENTIFIQUE (FR) | 1991-07-09 | — | — | US | disclosed |
| EP-0375527-A1 | N-aryl-azetidinones, process for their preparation and their use as elastase inhibitors | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1990-06-27 | — | — | EP | disclosed |