SCHEMBL3466699

SCHEMBL3466699

CCOCNc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.44
ALDH1A1 P00352 2/20 0.44
GAA P10253 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
GRM5 P41594 1/20 0.43
HTT P42858 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.39
LMNA P02545 2/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29200269 0.85 ALDH1A1 (0.52) MAPTALDH1A1HTTL3MBTL1LMNA
SCHEMBL15978899 0.83 ALDH1A1 (0.40) MAPTALDH1A1GAANPSR1GRM5
SCHEMBL11772285 0.83 HPGD (0.46) MAPTALDH1A1GAANPSR1HTT
Ether SCHEMBL28110624 0.82 LMNA (0.52) MAPTALDH1A1GAANPSR1HTT
SCHEMBL18852749 0.79 HPGD (0.43) MAPTALDH1A1GAANPSR1L3MBTL1
SCHEMBL11895182 0.79 ALDH1A1 (0.49) MAPTALDH1A1GAANPSR1HTT
SCHEMBL1420925 0.78 MAPT (0.52) MAPTALDH1A1NPSR1L3MBTL1LMNA
SCHEMBL12451087 0.78 MAPT (0.48) MAPTALDH1A1GAAHTTL3MBTL1
SCHEMBL27824745 0.78 F2 (0.41) MAPTALDH1A1GAAHTTL3MBTL1
SCHEMBL11895296 0.78 LTA4H (0.44) MAPTALDH1A1HTTLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111748214-A Antibacterial ABS plastic preparation process 田虹 2020-10-09 CN claimed
US-9000107-B2 Process for producing polydienes BRIDGESTONE CORPORATION (JP) 2015-04-07 US claimed
US-20120196995-A1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORPORATION (JP) 2012-08-02 US claimed
WO-2023084473-A1 BICYCLIC HETEROAROMATIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD. (IN) 2023-05-19 WO disclosed
US-9000107-B2 Process for producing polydienes BRIDGESTONE CORPORATION (JP) 2015-04-07 US disclosed
US-20120196995-A1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORPORATION (JP) 2012-08-02 US disclosed
US-7767690-B2 Amino alcohol derivatives and their use as renin inhibitor NOVARTIS AG (CH) 2010-08-03 US disclosed
US-20090118281-A1 Amino Alcohol Derivatives And Their Use As Renin Inhibitor NOVARTIS AG (CH) 2009-05-07 US disclosed
CN-1910136-A Organic compounds SPEEDEL EXPERIMENTA AG (CH) 2007-02-07 CN disclosed
US-20070021400-A1 Amino alcohols as therapeutic compounds SPEEDEL EXPERIMENTA AG (CH) 2007-01-25 US disclosed
EP-1745776-A1 Aminoalcohols as therapeutic compounds Speedel Experimenta AG (CH) 2007-01-24 EP disclosed
EP-1711456-A2 AMINO ALCOHOL DERIVATIVES AND THEIR USE AS RENIN INHIBITORS Speedel Experimenta AG (CH) 2006-10-18 EP disclosed
WO-2005070870-A2 AMINO ALCOHOL DERIVATIVES AND THEIR USE AS RENIN INHIBITORS SPEEDEL EXPERIMENTA AG (CH) 2005-08-04 WO disclosed
US-5719141-A HYPOTENSIVE AGENTS NOVARTIS CORPORATION (US) 1998-02-17 US disclosed
CN-1169986-A 2.9-diamino-and 2-amino-8-carbamoyl-4-hydroxy-aldanoic acid amide derivatives CIBA GEIGY AG (CH) 1998-01-14 CN disclosed
EP-0702004-A2 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives CIBA-GEIGY AG (CH) 1996-03-20 EP disclosed
EP-0361230-B1 Mixtures from polyamides, aromatic polycarbonates and maleic imide copolymeres and use of them as thermoplastic moulding compositions BAYER AG (DE) 1994-01-12 EP disclosed
EP-0361230-A2 Mixtures from polyamides, aromatic polycarbonates and maleic imide copolymeres and use of them as thermoplastic moulding compositions BAYER AG (DE) 1990-04-04 EP disclosed
US-3946071-A HERBICIDES MONSANTO COMPANY (US) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090118281-A1 Amino Alcohol Derivatives And Their Use As Renin Inhibitor REN, AGTR1, ADH1A MAPT 2542/4885ALDH1A1 161/4885GAA 2118/4885
US-20070021400-A1 Amino alcohols as therapeutic compounds CTSL, CTSD, CTSS MAPT 621/4885ALDH1A1 279/4885GAA 312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.