Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873568 | 0.86 | AGTR1 (0.49) | AGTR2AGTR1 | |
| SCHEMBL9873248 | 0.86 | AGTR1 (0.42) | AGTR2AGTR1 | |
| SCHEMBL9874581 | 0.83 | AGTR1 (0.33) | AGTR2AGTR1 | |
| SCHEMBL9874393 | 0.80 | AGTR1 (0.47) | AGTR2AGTR1 | |
| SCHEMBL9872292 | 0.79 | ALDH1A1 (0.41) | AGTR2AGTR1 | |
| SCHEMBL9874561 | 0.79 | PPARG (0.51) | AGTR2AGTR1 | |
| SCHEMBL9873127 | 0.78 | AGTR2 (0.38) | AGTR2AGTR1 | |
| SCHEMBL9874500 | 0.78 | AGTR1 (0.38) | AGTR2AGTR1 | |
| SCHEMBL9873002 | 0.78 | AGTR1 (0.38) | AGTR2AGTR1 | |
| SCHEMBL9872051 | 0.77 | AGTR1 (0.38) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019715-A1 | 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-26 | — | — | WO | disclosed |