Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 5/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | HRH2 | P25021 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 3/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030772 | 0.86 | PDK1 (0.71) | PDK1DRD3DRD2HRH2ADRA2A | |
| Bromide SCHEMBL1030770 | 0.85 | PDK1 (0.70) | PDK1DRD3DRD2HRH2ADRA2A | |
| SCHEMBL10687990 | 0.84 | PDK1 (0.53) | PDK1LMNAMAPTTSHRMAPK1 | |
| SCHEMBL10687999 | 0.84 | PDK1 (0.53) | PDK1LMNAMAPTTSHRMAPK1 | |
| SCHEMBL10687994 | 0.84 | PDK1 (0.53) | PDK1LMNAMAPTTSHRMAPK1 | |
| SCHEMBL9873084 | 0.83 | PDK1 (0.66) | PDK1DRD3DRD2HRH2ADRA2A | |
| SCHEMBL1033938 | 0.79 | SMN1; SMN2 (0.56) | PDK1LMNAMAPTTSHRHSD17B10 | |
| SCHEMBL3025573 | 0.77 | SCN4A (0.62) | DRD3DRD2HRH2ADRA2ADRD4 | |
| SCHEMBL1032097 | 0.76 | RAB9A (0.56) | PDK1LMNAPOLBMAPTMAPK1 | |
| SCHEMBL5810193 | 0.75 | SCN4A (0.61) | DRD3DRD2HRH2ADRA2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024010761-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2024-01-11 | — | — | WO | disclosed |
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |