Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875722 | 0.90 | RORC (0.35) | RORCCYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9874444 | 0.90 | RORC (0.35) | RORCCYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL10683398 | 0.77 | CYP2D6 (0.37) | CYP3A4CYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL9872276 | 0.76 | RORC (0.41) | RORCALDH1A1SMN1; SMN2LMNACTSL | |
| SCHEMBL9872800 | 0.75 | RORC (0.43) | RORCALDH1A1SMN1; SMN2LMNACTSL | |
| SCHEMBL9873530 | 0.74 | RORC (0.35) | RORCNR1H4CTSLCTSBCTSS | |
| SCHEMBL9873533 | 0.74 | RORC (0.35) | RORCNR1H4CTSLCTSBCTSS | |
| SCHEMBL9874253 | 0.74 | RORC (0.43) | RORCCYP3A4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10527742 | 0.73 | NPSR1 (0.34) | CYP3A4CYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL12131499 | 0.73 | GAA (0.41) | CYP3A4CYP2C9CYP2C19ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |