Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873533 | 1.00 | RORC (0.35) | RORCDHODHL3MBTL1NR1H4CTSL | |
| SCHEMBL9874444 | 0.85 | RORC (0.35) | RORCDHODHL3MBTL1NR1H4CTSL | |
| SCHEMBL9875722 | 0.85 | RORC (0.35) | RORCDHODHL3MBTL1NR1H4CTSL | |
| SCHEMBL9874569 | 0.81 | RORC (0.41) | RORCL3MBTL1CTSLCTSBCTSS | |
| SCHEMBL9873858 | 0.78 | RORC (0.42) | RORCCTSLCTSBCTSSGAA | |
| SCHEMBL9875004 | 0.74 | RORC (0.36) | RORCDHODHL3MBTL1NR1H4CTSL | |
| SCHEMBL8472008 | 0.73 | MAPT (0.41) | DHODHNR1H4GAAMAPTTDP1 | |
| SCHEMBL14356264 | 0.71 | NR1H4 (0.43) | DHODHL3MBTL1NR1H4CTSLCTSB | |
| SCHEMBL9872276 | 0.69 | RORC (0.41) | RORCL3MBTL1CTSLCTSBCTSS | |
| SCHEMBL9873493 | 0.69 | RORC (0.40) | RORCCTSLCTSBCTSSGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |