SCHEMBL9875223

SCHEMBL9875223

CCOC1(C)NOC(=O)C1N1C(=O)c2cccc3cccc(c23)C1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.42
CYP1B1 Q16678 1/20 0.42
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 3/20 0.40
HPGD P15428 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
HSD17B10 Q99714 2/20 0.39
HEXA P06865 4/20 0.37
HEXB P07686 4/20 0.37
CYP1A2 P05177 1/20 0.36
MAPT P10636 1/20 0.36
AKR1B1 P15121 1/20 0.36
ALOX15 P16050 1/20 0.36
OGA O60502 1/20 0.36
CASP1 P29466 1/20 0.36
MPI P34949 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9876170 0.74 KDM4E (0.42) CYP1B1ALDH1A1KDM4EHPGDMEN1
SCHEMBL13707191 0.66 TDP1 (0.73) TDP1CYP1B1ALDH1A1KDM4EHPGD
SCHEMBL18485418 0.63 ALDH1A1 (0.56) TDP1CYP1B1ALDH1A1KDM4EHPGD
SCHEMBL9541318 0.62 CYP1B1 (0.46) TDP1CYP1B1ALDH1A1KDM4EHPGD
SCHEMBL862546 0.62 ERCC1 (0.63) CYP1B1ALDH1A1KDM4EHPGDMEN1
SCHEMBL117049 0.61 CYP1B1 (1.00) CYP1B1ALDH1A1KDM4EHPGDMEN1
SCHEMBL4503768 0.60 CYP1B1 (0.55) CYP1B1ALDH1A1KDM4EHPGDMEN1
SCHEMBL11395567 0.60 PIN1 (0.75) CYP1B1ALDH1A1KDM4EHPGDMEN1
SCHEMBL9876255 0.59 ALDH1A1 (0.41) TDP1CYP1B1ALDH1A1KDM4EHPGD
SCHEMBL9035129 0.59 TDP1 (0.67) TDP1CYP1B1ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5076831-A Herbicides BASF AKTIENGESELLSCHAFT (DE) 1991-12-31 US disclosed