Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.35 |
| ▸ | CDK2 | P24941 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874916 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1ALDH1A1NPSR1HTT | |
| SCHEMBL9875417 | 0.78 | MEN1 (0.50) | SMN1; SMN2ALDH1A1NPSR1HTTMAPT | |
| SCHEMBL9874474 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1ALDH1A1NPSR1HTT | |
| SCHEMBL10457512 | 0.72 | MELK (0.40) | SMN1; SMN2L3MBTL1ALDH1A1HTTMAPT | |
| SCHEMBL9872674 | 0.71 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1NPSR1HTTMAPT | |
| SCHEMBL9874920 | 0.71 | TDP1 (0.47) | L3MBTL1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9873674 | 0.70 | KMT2A (0.42) | SMN1; SMN2ALDH1A1NPSR1HTTMAPT | |
| SCHEMBL7212183 | 0.68 | ALDH1A1 (0.53) | SMN1; SMN2L3MBTL1ALDH1A1HTTMAPT | |
| SCHEMBL9381137 | 0.67 | GABRP (0.39) | SMN1; SMN2L3MBTL1ALDH1A1HTTMEN1 | |
| SCHEMBL11264529 | 0.65 | TP53 (0.52) | SMN1; SMN2L3MBTL1ALDH1A1NPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |