SCHEMBL9876594

SCHEMBL9876594

CCCCCCCCCCCCCCC(C)CCCNC(=O)c1ccc(-n2oc(C(C)(C)C)c(COc3ccc(NC(=O)OC(C)(C)C)cc3)c2=O)c([N+](=O)[O-])c1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.41
ALDH1A1 P00352 7/20 0.41
LMNA P02545 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
GAA P10253 2/20 0.39
POLB P06746 1/20 0.36
SLC2A1 P11166 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
CD274 Q9NZQ7 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
PLA2G4B P0C869 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9877535 0.84 ALDH1A1 (0.48) MAPTALDH1A1LMNASMN1; SMN2GAA
SCHEMBL9864397 0.83 ALDH1A1 (0.48) MAPTALDH1A1LMNASMN1; SMN2GAA
Hydrochloric Acid SCHEMBL9864700 0.82 ALDH1A1 (0.48) MAPTALDH1A1LMNASMN1; SMN2GAA
SCHEMBL9876597 0.81 MAPT (0.34) MAPTALDH1A1LMNASMN1; SMN2MEN1
SCHEMBL9823387 0.76 ALDH1A1 (0.49) MAPTALDH1A1LMNASMN1; SMN2GAA
SCHEMBL9769708 0.74 LMNA (0.52) MAPTALDH1A1LMNASMN1; SMN2GAA
SCHEMBL9876485 0.68 LMNA (0.37) MAPTALDH1A1LMNASMN1; SMN2POLB
SCHEMBL6931497 0.67 GAA (0.47) MAPTALDH1A1LMNASMN1; SMN2GAA
SCHEMBL9769700 0.67 LMNA (0.56) MAPTALDH1A1LMNASMN1; SMN2GAA
SCHEMBL9769698 0.64 LMNA (0.50) MAPTALDH1A1LMNASMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5049477-A Image forming, etching, plating FUJI PHOTO FILM CO., LTD. (JP) 1991-09-17 US disclosed