SCHEMBL987674

SCHEMBL987674

C=CC(=O)C1=C(CC)C(=O)NC1=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.33
TSHR P16473 2/20 0.32
HPGD P15428 1/20 0.32
ALDH1A1 P00352 1/20 0.31
THRA P10827 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27607301 0.76 FGFR1 (0.31) ALDH1A1
Bicarbonate SCHEMBL3183819 0.71 FFAR3 (0.32) HPGDALDH1A1
SCHEMBL988700 0.70 LMNA (0.33)
SCHEMBL890999 0.65 XIAP (0.39)
SCHEMBL987863 0.60 ALDH1A1 (0.35) ALDH1A1
Triethylene Glycol SCHEMBL987901 0.59 MEN1 (0.41) THRBTSHRALDH1A1
SCHEMBL460153 0.59 ALDH1A1 (0.33) ALDH1A1
Triethylene Glycol SCHEMBL5699200 0.59 MEN1 (0.46) THRBTSHRALDH1A1
SCHEMBL13078829 0.57 MAPT (0.35) THRBHPGDALDH1A1
SCHEMBL4899025 0.55 THRB (0.72) THRBHPGDALDH1A1THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051665-B1 PHOTOPOLYMERIZATION COMPOSITIONS INCLUDING MALEIMIDES AND PROCESSES FOR USING THE SAME ALBEMARLE CORP (US) 2006-07-12 EP claimed
US-6555593-B1 Maleimides with a benzophenone compound/hydrogen atom donor sensitizer system activated by irradiation ALBEMARLE CORPORATION 2003-04-29 US claimed
US-20020019453-A1 Polymerization processes using aliphatic maleimides FIRST CHEMICAL CORPORATION 2002-02-14 US claimed
CN-1295680-A Photopolymerization compositions including maleimides and processes for using the same FIRST CHEMICAL CORP (US) 2001-05-16 CN claimed
EP-1051665-A1 PHOTOPOLYMERIZATION COMPOSITIONS INCLUDING MALEIMIDES AND PROCESSES FOR USING THE SAME First Chemical Corporation (US) 2000-11-15 EP claimed
WO-1999039247-A1 PHOTOPOLYMERIZATION COMPOSITIONS INCLUDING MALEIMIDES AND PROCESSES FOR USING THE SAME FIRST CHEMICAL CORPORATION (US) 1999-08-05 WO claimed
WO-1998007759-A9 POLYMERIZATION PROCESSES USING ALIPHATIC MALEIMIDES 1998-06-11 WO claimed
WO-1998007759-A1 POLYMERIZATION PROCESSES USING ALIPHATIC MALEIMIDES FIRST CHEMICAL CORPORATION (US) 1998-02-26 WO claimed
US-20220193459-A1 HYBRID NAIL COATING SYSTEMS AD METHODS OF THEIR USE NAIL ALLIANCE, LLC 2022-06-23 US disclosed
EP-1952184-B1 PHOTOCHROMIC MULTIFOCAL OPTICAL ARTICLE TRANSITIONS OPTICAL INC (US) 2021-08-11 EP disclosed
US-20180001116-A1 HYBRID NAIL COATING SYSTEMS AND METHODS OF THEIR USE NAIL ALLIANCE, LLC (US) 2018-01-04 US disclosed
US-20170189316-A1 HYBRID NAIL COATING SYSTEMS AND METHODS OF THEIR USE NAIL ALLIANCE, LLC 2017-07-06 US disclosed
US-9526686-B2 Compositions for removable gel applications for nails and methods of their use NAIL ALLIANCE, LLC (US) 2016-12-27 US disclosed
EP-2995217-A1 COMPOSITIONS FOR REMOVABLE GEL APPLICATIONS FOR NAILS AND METHODS OF THEIR USE Nail Alliance LLC (US) 2016-03-16 EP disclosed
CN-1295680-A Photopolymerization compositions including maleimides and processes for using the same FIRST CHEMICAL CORP (US) 2001-05-16 CN disclosed
EP-1051665-A1 PHOTOPOLYMERIZATION COMPOSITIONS INCLUDING MALEIMIDES AND PROCESSES FOR USING THE SAME First Chemical Corporation (US) 2000-11-15 EP disclosed
US-6034150-A Polymerization processes using aliphatic maleimides UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2000-03-07 US disclosed
WO-1999039247-A1 PHOTOPOLYMERIZATION COMPOSITIONS INCLUDING MALEIMIDES AND PROCESSES FOR USING THE SAME FIRST CHEMICAL CORPORATION (US) 1999-08-05 WO disclosed
WO-1998007759-A9 POLYMERIZATION PROCESSES USING ALIPHATIC MALEIMIDES 1998-06-11 WO disclosed
WO-1998007759-A1 POLYMERIZATION PROCESSES USING ALIPHATIC MALEIMIDES FIRST CHEMICAL CORPORATION (US) 1998-02-26 WO disclosed