Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 3/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL9236884 | 0.93 | LMNA (0.40) | ACHEHTR6HRH3POLBNPSR1 | |
| Fumaric Acid SCHEMBL9236891 | 0.93 | LMNA (0.40) | ACHEHTR6HRH3POLBNPSR1 | |
| SCHEMBL9876809 | 0.83 | HRH3 (0.49) | AGERHRH3POLBNPSR1ALDH1A1 | |
| SCHEMBL9230726 | 0.81 | GSK3B (0.42) | ACHEHRH3SMN1; SMN2CYP1A2CYP2D6 | |
| Fumaric Acid SCHEMBL9232352 | 0.76 | HRH3 (0.46) | ACHEHRH3POLBNPSR1ALDH1A1 | |
| Maleic Acid SCHEMBL9232346 | 0.76 | HRH3 (0.46) | ACHEHRH3POLBNPSR1ALDH1A1 | |
| SCHEMBL9234490 | 0.76 | GSK3B (0.50) | HRH3ALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9876897 | 0.75 | KDM4E (0.42) | ACHEAGERPOLBNPSR1GAA | |
| SCHEMBL9876899 | 0.74 | CXCR1 (0.45) | AGERHRH3NPSR1GAASMN1; SMN2 | |
| SCHEMBL9877191 | 0.74 | ADORA3 (0.41) | POLBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |