Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9236122 | 0.92 | ADORA3 (0.42) | ADORA3KCNH2MAPTRXFP1KAT2B | |
| Fumaric Acid SCHEMBL9236129 | 0.92 | ADORA3 (0.42) | ADORA3KCNH2MAPTRXFP1KAT2B | |
| SCHEMBL9236247 | 0.79 | KAT2B (0.44) | ADORA3KCNH2MAPTKAT2BNAMPT | |
| SCHEMBL9877149 | 0.79 | NAMPT (0.53) | KAT2BNAMPTCYP2C19 | |
| SCHEMBL9876892 | 0.76 | KAT2B (0.42) | KAT2BPOLBCYP2C19 | |
| SCHEMBL9876982 | 0.76 | GAA (0.48) | MAPTKAT2BKMT2ANAMPTPOLB | |
| SCHEMBL9876863 | 0.74 | ACHE (0.41) | POLBCYP2C19 | |
| Fumaric Acid SCHEMBL9232280 | 0.72 | NAMPT (0.52) | MAPTKAT2BKMT2ANAMPTPOLB | |
| Maleic Acid SCHEMBL9232273 | 0.72 | NAMPT (0.52) | MAPTKAT2BKMT2ANAMPTPOLB | |
| SCHEMBL9235819 | 0.70 | KDM4E (0.47) | L3MBTL1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |