Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876890 | 0.80 | PTGER1 (0.50) | CCNE1CDK2MEN1KMT2AGAA | |
| SCHEMBL9876889 | 0.76 | CCNE1 (0.46) | CCNE1CDK2MEN1KMT2AGAA | |
| SCHEMBL9877134 | 0.74 | TP53 (0.36) | MEN1KMT2AGAAMAPTPOLB | |
| SCHEMBL9876850 | 0.72 | MAPT (0.47) | CCNE1CDK2MEN1KMT2AGAA | |
| SCHEMBL14132947 | 0.71 | ALDH1A1 (0.56) | CDK2MEN1KMT2AGAAMAPT | |
| SCHEMBL9876720 | 0.69 | CDK2 (0.46) | CCNE1CDK2MEN1KMT2AMAPT | |
| SCHEMBL9876798 | 0.69 | CDK2 (0.51) | CCNE1CDK2MEN1KMT2AGAA | |
| SCHEMBL11093684 | 0.69 | OPRD1 (0.46) | CCNE1CDK2MEN1KMT2AGAA | |
| SCHEMBL23401122 | 0.68 | RPA1 (0.52) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL21208570 | 0.68 | SMN1; SMN2 (0.51) | MEN1KMT2AMAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0338087-A1 | FUSED PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-10-25 | — | — | EP | disclosed |