Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.39 |
| ▸ | CDK2 | P24941 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9235819 | 0.94 | KDM4E (0.47) | PTGER1CCNA2CDK2KDM4ERAB9A | |
| SCHEMBL9877149 | 0.82 | NAMPT (0.53) | KAT2BCYP2C19KDM4EHPGDTLR9 | |
| SCHEMBL9876882 | 0.80 | LSS (0.52) | PTGER1CYP2C19CCNA2CDK2TOP2A | |
| SCHEMBL9236247 | 0.78 | KAT2B (0.44) | KAT2BKDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL9876810 | 0.77 | TNK2 (0.46) | PTGER1CYP2C19CCNA2CDK2 | |
| Maleic Acid SCHEMBL9232273 | 0.76 | NAMPT (0.52) | KAT2BCYP2C19KDM4ERAB9AALDH1A1 | |
| Fumaric Acid SCHEMBL9232280 | 0.76 | NAMPT (0.52) | KAT2BCYP2C19KDM4ERAB9AALDH1A1 | |
| SCHEMBL9877191 | 0.76 | ADORA3 (0.41) | KAT2BCYP2C19POLB | |
| SCHEMBL9876805 | 0.76 | LMNA (0.44) | RAB9AALDH1A1HPGD | |
| SCHEMBL9234476 | 0.75 | TNK2 (0.44) | PTGER1CCNA2CDK2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |