Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10528943 | 0.84 | CA2 (1.00) | CA2ALDH1A1MAPTKMT2AGAA | |
| SCHEMBL9574410 | 0.78 | CA2 (0.49) | CA2ALDH1A1MAPTKMT2AGSTP1 | |
| SCHEMBL10669752 | 0.78 | CA2 (0.63) | CA2ALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL832001 | 0.78 | ALDH1A1 (0.71) | CA2ALDH1A1MAPTL3MBTL1HTT | |
| SCHEMBL9877837 | 0.77 | CA2 (0.50) | CA2ALDH1A1MAPTRAB9AHTT | |
| SCHEMBL10529622 | 0.77 | CA2 (1.00) | CA2ALDH1A1SMN1; SMN2GSTP1GSTM2 | |
| SCHEMBL9404105 | 0.77 | VCAM1 (0.63) | ALDH1A1 | |
| SCHEMBL12291532 | 0.77 | CA2 (0.63) | CA2ALDH1A1MAPTL3MBTL1RAB9A | |
| SCHEMBL8285548 | 0.77 | CA2 (0.63) | CA2ALDH1A1MAPTL3MBTL1RAB9A | |
| SCHEMBL11876450 | 0.77 | CA2 (0.68) | CA2ALDH1A1MAPTL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |