Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853650 | 0.83 | RAPGEF4 (0.38) | L3MBTL1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL9878800 | 0.83 | RAPGEF4 (0.38) | L3MBTL1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL9878286 | 0.81 | MAPT (0.60) | MAPTALDH1A1GAAPOLBRECQL | |
| SCHEMBL9879146 | 0.81 | CYP19A1 (0.40) | L3MBTL1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL9877842 | 0.79 | L3MBTL1 (0.46) | L3MBTL1P2RY4PRMT1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL10632546 | 0.78 | L3MBTL1 (0.45) | L3MBTL1P2RY4PRMT1MAPTALDH1A1 | |
| SCHEMBL9350920 | 0.74 | RAPGEF4 (0.42) | L3MBTL1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL9878469 | 0.74 | KMT2A (0.42) | MAPTALDH1A1KDM4ENSD2LMNA | |
| SCHEMBL9878782 | 0.73 | RAPGEF4 (0.41) | L3MBTL1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL19381162 | 0.70 | ADORA2A (0.47) | L3MBTL1PRMT1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |